Modified p53 constructs which enhance DNA binding
US5847083A · kind A · utility
3Cited by
3References
18Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Aug 21, 1996 |
| Grant date | Dec 8, 1998 |
| Priority date | — |
| Expiry date | Aug 21, 2016 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K48/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A modified p53 protein or peptide having DNA binding in which amino acid residue 284 of a p53 protein or protein fragment is changed to Arginine or Lysine, is described. Also described are nucleotide sequences encoding the modified protein and vectors capable of expressing it.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.