Imide derivatives for inhibiting the production of interleukin-1.beta. and the production of tumor necrosis factor .alpha.
US5847123A · kind A · utility
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2References
10Claims
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Key dates
| Filing date | Jul 1, 1997 |
| Grant date | Dec 8, 1998 |
| Priority date | — |
| Expiry date | Jul 1, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D333/38
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Imide compounds having a propioloyl group or pharmaceutically acceptable salts thereof which exhibit potent activities to inhibit the production of Interleukin 1-.beta. and also the production of Tumor Necrosis Factor .alpha.. These imide compounds are useful as a prophylactic or therapeutic agent for inhibiting the production of Interleukin 1-.beta. and the production of Tumor Necrosis Factor .alpha., typically for such diseases as chronic rheumatism, sepsis, ulcerative colitis, Crohn's disease and many other related diseases in which Interleukin 1-.beta. and/or Tumor Necrosis Factor .alpha. would participate.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.