Hollow fiber blood purifying membrane and process for its production
US5849189A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Nov 6, 1995 |
| Grant date | Dec 15, 1998 |
| Priority date | — |
| Expiry date | Nov 6, 2015 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01D71/16
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
A hollow fiber blood purifying membrane which is a hollow fiber membrane substantially composed of cellulose acetate, has a substantially non-oriented distribution of cellulose acetate polymer particles on the inner surface of the hollow fibers, has a dense layer with a thickness in the range of 30-1000 nm on both the inner and outer surface of the hollow fibers and a porous structure which is substantially uniform at the membrane wall between the two dense layers, and has an in vitro ultrafiltration rate (UFR) of 10 to 50 ml/m.sup.2 .multidot.mmHg.multidot.hr and a (in vivo UFR)/(in vitro UFR) ratio of at least 0.3, a blood plasma albumin permeation blockage of at least 90%, and an in vivo .beta..sub.2 -microglobulin (.beta..sub.2 -MG) sieving coefficient of at least 0.4, as well as a process for its production.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.