Nucleic acid encoding a NF-.kappa.B activation regulatory protein, I.kappa.B.beta.
US5849580A · kind A · utility
6Cited by
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9Claims
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Key dates
| Filing date | Nov 13, 1996 |
| Grant date | Dec 15, 1998 |
| Priority date | — |
| Expiry date | Nov 13, 2016 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K47/26
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a novel polypeptide, I.kappa.B-.beta., which binds to and affects NF-.kappa.B gene activation. Also provided is the nucleotide sequence encoding I.kappa.B-.beta. and methods of identifying compositions which affect I.kappa.B-.beta./NF-.kappa.B complexes. Methods of treatment of disorders associated with NF-.kappa.B induced gene activation are also described herein.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.