Stable and bioactive modified porcine somatotropin and pharmaceutical compositions thereof
US5849694A · kind A · utility
3Cited by
9References
4Claims
0Family size
Inventors
Key dates
| Filing date | Jul 16, 1990 |
| Grant date | Dec 15, 1998 |
| Priority date | — |
| Expiry date | Jul 16, 2010 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S930/12
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a stable and bioactive recombinant small-loop modified somatotropin which has its small-loop cysteines changed to other amino acids or deleted altogether and a method for producing such a small-loop modified somatotropin. Also provided by the present invention are DNA sequences coding for such small-loop modified somatotropins, plasmids containing such sequences, and organisms containing such plasmids. Furthermore, pharmaceutical compositions including small-loop modified somatotropins and methods for using such pharmaceutical compositions are disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.