Pyrrolyl tetrahydrobenzoquinoxaline diones, their preparation and use as glutamate receptor antagonist

US5849744A · kind A · utility

Assignee

• BASF SE

Inventors

• Wilfried Lubisch · Mannheim, DE
• Michael Vierling · Ludwigshafen, DE
• Berthold Behl · Ludwigshafen, DE
• Hans P. Hofmann · Schifferstadt, DE

Key dates

• Filing date: Mar 27, 1997
• Grant date: Dec 15, 1998
• Expiry date: Mar 27, 2017

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Pyrrolyltetrahydrobenzoquinoxalinediones of the formula I ##STR1## and their tautomeric and isomeric forms, and their physiologically tolerated salts, in which the variables have the meanings stated in the description, and the preparation thereof are described. The novel compounds are antagonists of the glutamate receptor subtypes and are thus suitable for controlling various diseases.