Crystal modification of CDCH a process for its preparation and pharmaceutical formulations comprising this modification

US5849752A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Alfons Grunenberg · Wuppertal, DE
• Patrick Bosche · Odenthal, DE

Key dates

• Filing date: Dec 5, 1996
• Grant date: Dec 15, 1998
• Expiry date: Dec 5, 2016

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P31/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The invention relates to the new monohydrate of 1-cyclopropyl-7-(S,S!-2,8-diazabicyclo-4.3.0!non-8-yl)6-fluoro-1,4-dihyd ro-8-methoxy-4-oxo-3-quinolinecarboxylic acid hydrochloride (CDCH), a process for its preparation and pharmaceutical formulations which comprise this monohydrate as the active compound.