3-amidochromanylsulfonyl(thio)ureas, processes for their preparation, their use, and pharmaceutical preparations comprising them

US5849755A · kind A · utility

Assignee

• Hoechst GmbH · DE

Inventors

• Heinrich Englert · Hofheim, DE
• Uwe Gerlach · Hattersheim, DE
• Dieter Mania · Königstein, DE
• Wolfgang Linz · Mainz, DE
• Heinz Gogelein · Frankfurt am Main, DE
• Erik Klaus · Kelkheim, DE

Key dates

• Filing date: Nov 13, 1997
• Grant date: Dec 15, 1998
• Expiry date: Nov 13, 2017

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D311/70
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

3-amidochromanylsulfonyl(thio)ureas of the formula (I): ##STR1## which are valuable pharmaceutically active compounds for the treatment of disturbances of the cardiovascular system, in particular for the treatment of arrhythmias, for preventing sudden cardiac death or for influencing a reduced contractility of the heart, and processes for their preparation, their use and pharmaceutical preparations comprising them.