Antagonists of gonadotropin releasing hormone

US5849764A · kind A · utility

Assignee

• MERCK & CO., INC. · US

Inventors

• Mark Goulet · Westfield, US
• Lin Chu · Scotch Plains, US
• Thomas F. Walsh · Stoneham, US
• Michael H. Fisher · Bound Brook, US
• Narindar N. Girotra · Old Bridge, US
• Matthew J. Wyvratt · Mountainside, US
• Peter Lin · Luzhu District, TW
• Wallace T. Ashton · Edison, US

Key dates

• Filing date: Dec 5, 1996
• Grant date: Dec 15, 1998
• Expiry date: Dec 5, 2016

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D471/04
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

There are disclosed compounds of formula (I) ##STR1## and pharmaceutically acceptable salts thereof which are useful as antagonists of GnRH and as such may be useful for the treatment of a variety of sex-hormone related and other conditions in both men and women.