N-arylalkyl-N-heteroarylurea and guandine compounds and methods of treating HIV infection

US5849769A · kind A · utility

Assignee

• MEDIVIR AB · SE

Inventors

• Peter Lind · Huddinge, SE
• Rolf Noreen · Huddinge, SE
• John Michael Morin, Jr. · Brownsburg, US
• Robert J. Ternansky · San Diego, US

Key dates

• Filing date: May 3, 1996
• Grant date: Dec 15, 1998
• Expiry date: May 3, 2016

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D401/12
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A method for treating HIV which comprises a compound of the formula ##STR1## wherein A is ##STR2## and Z.sub.i is O, Se, NR.sup.a or C(R.sup.a).sub.2, and PA1 Z.sub.ii is --O or (.dbd.O).sub.2 ; wherein PA1 R.sub.1, R.sub.2, R.sub.3, and R.sub.4 are as defined in the specification.