Hybridomas producing monoclonal antibodies to new mucin epitopes
US5849876A · kind A · utility
56Cited by
21References
3Claims
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Key dates
| Filing date | Jan 11, 1994 |
| Grant date | Dec 15, 1998 |
| Priority date | — |
| Expiry date | Jan 11, 2014 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Novel hybridoma cell lines producing monoclonal antibodies reactive with purified mucin antigens from normal and tumor sources are generated using mucins, including purified mucins from tumor sources. Epitopes on mucin antigens from normal and tumor sources are demonstrated to be distinct, using these new antibodies. The antibodies may be useful alone or in combination, in the diagnosis and treatment of cancer including malignancies of the breast and lung.
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