Patent · US Expired

Peptidyl compounds and their therapeutic use as inhibitors of metalloproteinases

US5853623A · kind A · utility

6Cited by
1References
10Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMay 10, 1996
Grant dateDec 29, 1998
Priority date
Expiry dateMay 10, 2016

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S530/868
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention concerns novel mercaptoalkylpeptidyl compounds of formula (I) which are useful inhibitors of matrix metalloproteinase and/or TNF-mediated diseases including degenerative diseases and certain cancers. The invention also concerns methods of treating patients suffering from disorders or diseases which can be attributed to or are associated with matrix metalloproteinase or TNF activity.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.