Large scale genotyping of diseases and a diagnostic test for spinocerebellar ataxia type 6
US5853995A · kind A · utility
39Cited by
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3Claims
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Key dates
| Filing date | Jan 7, 1997 |
| Grant date | Dec 29, 1998 |
| Priority date | — |
| Expiry date | Jan 7, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q2600/156
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The present invention provides a method of screening individuals at risk for developing diseases caused by trinucleotide repeat sequence instability. Specifically, the present invention is drawn to screening individuals at risk for developing autosomal dominant spinocerebellar ataxia type 6 by determining the length of a CAG trinucleotide repeat in the .alpha..sub.1A calcium channel gene of the individual. In addition, there is provided a method of identifying genes which are disease-causing due to trinucleotide repeat sequence instability by large scale genotyping.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.