Myoglobin with peroxidase activity
US5854041A · kind A · utility
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Key dates
| Filing date | Sep 16, 1996 |
| Grant date | Dec 29, 1998 |
| Priority date | — |
| Expiry date | Sep 16, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/4716
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Myoglobin is shown to have Manganese (Mn.sup.2') binding and peroxidase capacity. Mn binding and peroxidase activity is enhanced by modification of the amino acid sequence of myoglobin to provide a Mn binding site on the surface of the protein near the heme group. Peroxidase activity of myoglobin not specific to Mn is enhanced by substituting amino acids at residues 39, 45, 46, 97 and 107 of myolglobin.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.