Sialyl Le.sup.x analogues as inhibitors of cellular adhesion
US5854218A · kind A · utility
46Cited by
8References
5Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Oct 15, 1996 |
| Grant date | Dec 29, 1998 |
| Priority date | — |
| Expiry date | Oct 15, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H15/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention relates to analogues of sialyl Le.sup.x that inhibit cellular adhesion between a selectin and cells that express sialyl Le.sup.x on their surfaces, as well as methods and compositions using the same, intermediates and methods for the preparation of the cellular adhesion inhibitor compounds and their intermediates. A contemplated intermediate or inhibitor compound has a structure that corresponds to that of Formula A, ##STR1##
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.