Simple method for the purification of a bioelastic polymer
US5854387A · kind A · utility
Assignees
Inventors
Key dates
| Filing date | Oct 13, 1995 |
| Grant date | Dec 29, 1998 |
| Priority date | — |
| Expiry date | Oct 13, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K14/001
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A method for purifying an artificial polymer that exhibits a reversible inverse temperature transition is provided. The method involves (a) dissolving the polymer in an aqueous medium so that the temperature of the medium is below the effective transition temperature; (b) adjusting the temperature of the aqueous medium relative to the effective transition temperature of the polymer; (c) removing any particulate material from the medium; (d) adjusting the temperature of the aqueous medium relative to the effective transition temperature of the polymer so that the temperature of the medium is above the effective transition temperature; (e) collecting the polymer from the medium as a more dense phase; and (f) optionally repeating any of steps (a)-(e) until a desired level or purity is reached; with the proviso the order of steps can be (a)-(d)-(e)-(a)-(b)-(c).
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.