Patent · US Expired

Method for making encapsulated gas microspheres from heat denatured protein in the absence of oxygen gas

US5855865A · kind A · utility

63Cited by
34References
7Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJul 2, 1997
Grant dateJan 5, 1999
Priority date
Expiry dateJul 2, 2017

Classification

  • Technology area (CPC B)Performing Operations; Transporting
  • CPC primaryB01J13/02
  • WIPO fieldChemical engineering
  • WIPO sectorChemistry

Abstract

Elastic protein microspheres, filled with water insoluble gases, have been produced by ultrasound and mechanical cavitation without the present of oxygen. The microspheres are highly echogenic. The microspheres exhibit greatly enhanced static pressure stability, up to 40 psig. The microspheres are resistant to coalescence and to expansion due to differential gas diffusion. The microspheres are resistant to collapse when suspended in a gas-depleted aqueous solution.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.