Compositions and methods of developing oligonucleotides and oligonucleotide analogs having antiviral activity
US5856085A · kind A · utility
7Cited by
3References
34Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 1, 1995 |
| Grant date | Jan 5, 1999 |
| Priority date | — |
| Expiry date | Dec 1, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12Q1/6811
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Methods of identifying and preparing anti-infectious agent compounds comprising the steps of incubating single stranded nucleic acids or nucleic acid analogs in the presence of infectious agents, selecting for nucleic acids or nucleic acid analogs which bind infectious agents, amplifying selected nucleic acids or nucleic acid analogs, repeating the selection steps and assaying for anti-infection activity are disclosed. Compositions that have anti-infectious activity against Rous sarcoma virus are also disclosed. Methods of identifying anti-tumor agent compounds are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.