Patent · US Expired

Structural gene of pneumococcal protein

US5856170A · kind A · utility

5Cited by
2References
24Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJun 6, 1995
Grant dateJan 5, 1999
Priority date
Expiry dateJun 6, 2015

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S530/825
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

A purified pneumococcal surface protein A (PspA) comprises a truncated form of the PspA protein which is immunoprotective and contains the protective epitopes of PspA. The PspA protein is soluble in physiologic solution and lacks at least the cell membrane anchor region of the whole protein. The protein is formed by insertion-duplication of mutagenesis of S. pneumoniae with pspA gene and expression of the truncated protein into the growth medium.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.