Patent · US Expired

Unsaturated hydroxyalkylquinoline acids as leukotriene antagonists

US5856322A · kind A · utility

11Cited by
10References
18Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 8, 1996
Grant dateJan 5, 1999
Priority date
Expiry dateFeb 8, 2016

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D215/12
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Compounds having the formula I: ##STR1## are leukotriene antagonists and inhibitors of leukotriene biosynthesis. These compounds are useful as anti-asthmatic, anti-allergic, anti-inflammatory, and cytoprotective agents. They are also useful in treating angina, cerebral spasm, glomerular nephritis, hepatitis, endotoxemia, uveitis, and allograft rejection.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.