Use of xanthine derivatives for the inhibition of dephosphorylation of cofilin

US5856330A · kind A · utility

Assignee

• Hoechst GmbH · DE

Inventors

• Stefan Mullner · Langenfeld, DE
• Claudia Dax · Gernsheim, DE

Key dates

• Filing date: Jul 23, 1997
• Grant date: Jan 5, 1999
• Expiry date: Jul 23, 2017

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y02A50/30
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds of the formula I ##STR1## where one of the radicals R.sup.1 and R.sup.3 is a radical of the formula II --(CH.sub.2).sub.n --A--CH.sub.3 (II) in which A is a covalent bond, --C(O)-- or --C(R.sup.4)(OH)--, are suitable for the production of pharmaceuticals for the modulation of apoptosis. A combination preparation comprising a compound of the formula I and a compound of the formula IV and/or V ##STR2## is suitable for the production of pharmaceuticals for the modulation of apoptosis.