Method for stabilizing pranoprofen and stable liquid preparation of pranoprofen
US5856345A · kind A · utility
11Cited by
5References
13Claims
0Family size
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Inventors
Key dates
| Filing date | Jan 7, 1997 |
| Grant date | Jan 5, 1999 |
| Priority date | — |
| Expiry date | Jan 7, 2017 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10T428/1393
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for stabilizing pranoprofen, comprising placing an aqueous solution of pranoprofen in coexistence with an antioxidant, or placing an aqueous solution of pranoprofen under the conditions of limited supply of oxygen, and a stable aqueous preparation of pranoprofen, comprising pranoprofen and an antioxidant. According to the present invention, the decomposition of pranoprofen in an aqueous solution of pranoprofen is remarkably suppressed. In particular, pranoprofen becomes stable to light, thus permitting long-term preservation of an aqueous solution, specifically a liquid preparation, of pranoprofen.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.