Patent · US Expired

Thyroxine/cyclodextrin complexes and pharmaceutical compositions containing the same

US5856359A · kind A · utility

11Cited by

5References

16Claims

0Family size

Assignee

Hexal AG · DE

Inventors

Wilfried Fischer · Holzkirchen, DE
Daniel Bracher · Muri, CH

Key dates

Filing date	Jul 24, 1997
Grant date	Jan 5, 1999
Priority date	—
Expiry date	Jul 24, 2017

Classification

Technology area (CPC B)Performing Operations; Transporting
CPC primaryB82Y5/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Thyroxine containing pharmaceutical compositions with improved aqueous solubility, stability and enhanced membrane permeation have been prepared by formulating thyroxine with cyclodextrins. These thyroxine/cyclodextrin complexes can further be transformed into different dosage forms (oral tablets, injectables, transdermal patches, hydrogels, ointments, suppositories etc.) by employing known, common pharmaceutical additives.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.