Patent · US Expired

Synthesis of 2-(methysulfonyl)-5-(trifluoro-methyl)-,3,4-thiadiazole via oxidation of 2-(methylthio)-5-(trifluoromethyl)-1,3,4-thiadiazole with glacial acetic acid

US5856499A · kind A · utility

0Cited by

2References

10Claims

0Family size

Assignee

BAYER HEALTHCARE LLC · DE

Inventors

Vidyanatha A. Prasad · Leawood, US
Jacqueline M. Applegate · Parkville, US
Klaus Jelich · Wuppertal, DE
Achim Noack · Leichlingen, DE

Key dates

Filing date	Dec 12, 1997
Grant date	Jan 5, 1999
Priority date	—
Expiry date	Dec 12, 2017

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D285/125
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

The present invention provides a process for making thiadiazole sulfones. The present process is used to make 2-(methylsulfonyl)-5-(trifluoromethyl)-1,3,4-thiadiazole. 2-(Methylsulfonyl)-5-(trifluoromethyl)-1,3,4-thiadiazole is made using catalytic oxidation in the presence of a suitable oxidizing agent. The catalyst used for the oxidation reaction is glacial acetic acid.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.