In vivo polymerizable ophthalmic compositions
US5858345A · kind A · utility
Assignees
Inventors
Key dates
| Filing date | Apr 8, 1997 |
| Grant date | Jan 12, 1999 |
| Priority date | — |
| Expiry date | Apr 8, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08F22/1006
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Ophthalmic compositions containing biocompatible, bioadhesive polymerizable amphipathic mesophase materials useful for repairing retinal tissue tears or retinal detachments are disclosed. In one embodiment, the polymerizable materials, which comprise substituted fluoroalkyl or perfluoroalkyl monomers having anionic, cationic, and/or nonionic surface active functionality in the unsaturated fluorophobic ends, are polymerized in vivo to provide effective, long-lasting repair of torn, ruptured or detached retinal tissue. Ophthalmic applications of these materials are not limited to retinal repair.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.