Hydrolyzed cellulose granulations for pharmaceuticals
US5858409A · kind A · utility
51Cited by
14References
7Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 17, 1996 |
| Grant date | Jan 12, 1999 |
| Priority date | — |
| Expiry date | Apr 17, 2016 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/2054
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The present invention provides a method for preparing a spray-dried compressible granular formulation for preparing pharmaceutical tablets in which hydrolyzed cellulose is used as a granulation aid, the resulting granulations, and pharmaceutical tablets compressed from such granules. In these formulations there is employed from 1 to 97% by weight pharmaceutical active, from about 3 to 99% by weight hydrolyzed cellulose, based on the dry weight of the granulation, and optionally conventional granulation and/or tableting additives such as surfactants, disintegrants and antiadherents/flow aids.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.