SF caspase-1 and compositions for making and methods of using the same
US5858778A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Dec 27, 1996 |
| Grant date | Jan 12, 1999 |
| Priority date | — |
| Expiry date | Dec 27, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N9/6475
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A substantially pure protein, Caspase-1, is disclosed. An isolated nucleic acid molecule that comprises a nucleic acid sequence that encodes Caspase-1, is disclosed. An isolated nucleic acid molecule consisting of a nucleic acid sequence that encodes Caspase-1, or a fragment thereof having at least 10 nucleotides is disclosed. Recombinant expression vector comprising a nucleic acid sequence that encodes Caspase-1 and host cells comprising the recombinant expression vector are disclosed. Oligonucleotide molecule comprising a nucleotide sequence complimentary to a nucleic acid sequence that encodes Caspase-1 of at least 5 nucleotides are disclosed. Antibodies that binds to an epitope on Caspase-1 are disclosed. Methods of identifying modulators and substrates of Caspase-1 are disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.