Patent · US Expired

Composition for treating mastitis and other staphylococcal infections

US5858962A · kind A · utility

16Cited by
1References
14Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 16, 1993
Grant dateJan 12, 1999
Priority date
Expiry dateDec 16, 2013

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12Y304/24075
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Lysostaphin is used to eliminate and cure staphylococcal infections including the cure of mastitis by intramammary infusion. Administration of from 2 mg to 400 mg of lysostaphin to an infected bovine mammary gland eliminates staphylococci, and the reoccurrence common with antibiotic therapy is not observed. Teat-dips containing lysostaphin, mutanolysin and lysozyme can be used as a prophylactic. Synergistic enhancement of the killing effect of lysostaphin is observed when a mild surfactant or penicillin or both is included in the formulation.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.