Antidiabetic agents

US5859051A · kind A · utility

Assignee

• MERCK & CO., INC. · US

Inventors

• Alan D. Adams · Cranford, US
• Gregory D. Berger · Montgomery, US
• Jeffrey P. Bergman · Tenafly, US
• Joel Berger · Hoboken, US
• Wei Han · Beaverton, US
• Mark D. Leibowitz · Millburn, US
• David E. Moller · Bedminster, US
• Conrad Santini · Hackettstown, US
• Soumya P. Sahoo · Old Bridge, US
• Richard L. Tolman · Hackettstown, US
• Jonthan R. Young

Key dates

• Filing date: Jan 31, 1997
• Grant date: Jan 12, 1999
• Expiry date: Jan 31, 2017

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D311/16
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

The instant invention is concerned with acetylphenols which are useful as antiobesity and antidiabetic compounds. Compositions and methods for the use of the compounds in the treatment of diabetes and obesity and for lowering or modulating triglyceride levels and cholesterol levels or raising high density lipoprotein levels or for increasing gut motility or for treating atherosclerosis are also disclosed.