Transcription factor DP-3 and isoforms thereof
US5859199A · kind A · utility
4Cited by
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2Claims
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Assignee
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Key dates
| Filing date | Sep 30, 1996 |
| Grant date | Jan 12, 1999 |
| Priority date | — |
| Expiry date | Sep 30, 2016 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N33/574
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The invention provides polypeptides of transcription factor DP-3 which exists in four isoforms produced by alternative splicing of mRNA, nucleic acid encoding the polypeptides and the use of such nucleic acid and polypeptides in assays. Two isoforms of DP-3 contain a region, designated the E region, which is a nuclear localization signal and is involved in a further level of regulation of DP-3 and its ability to bind to E2F-1 and regulate the cell cycle.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.