Human basic fibroblast growth factor analog
US5859208A · kind A · utility
41Cited by
1References
1Claims
0Family size
Inventors
Key dates
| Filing date | Feb 12, 1990 |
| Grant date | Jan 12, 1999 |
| Priority date | — |
| Expiry date | Feb 12, 2010 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2830/55
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A human basic fibroblast growth factor (FGF) protein analog wherein the cysteine at positions 78 and 96 is replaced by serine, and said analog exhibits the biological activity of native, human basic FGF. The DNA sequences encoding analogs of human acidic and basic fibroblast growth factors (FGF) can be recombinantly expressed to obtain practical amounts of proteins useful in effecting both pathologies related to persistent angiogenesis and wound healing and related tissue repair.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.