DTPA monoamides, pharmaceutical agents containing these compounds, their use and process for their production

US5859214A · kind A · utility

Assignee

• SCHERING CORPORATION · US

Inventors

• Heinz Gries · Berlin, DE
• Erich Klieger · Berlin, DE
• Bernd Raduchel · Berlin, DE
• Heribert Schmitt-Willich · Berlin, DE
• Hanns-Joachim Weinmann · Berlin, DE
• Hubert Vogler · Berlin, DE
• Gabriele Schuhmann-Giampieri · Berlin, DE
• Jurgen Conrad · Berlin, DE

Key dates

• Filing date: Apr 15, 1994
• Grant date: Jan 12, 1999
• Expiry date: Apr 15, 2014

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07F15/025
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds of general formula I ##STR1## wherein Z.sup.1, Z.sup.2, X, R.sup.2 and R.sup.3 are as herein defined, are valuable pharmaceutical agents. In particular, the compounds are useful as contrast agents in NMR diagnosis.