Prf protein and nucleic acid sequences: compositions and methods for plant pathogen resistance

US5859351A · kind A · utility

Assignee

• The Regents of the University of California · US

Inventors

• Brian S. Staskawicz · Castro Valley, US
• Giles Edward Oldroyd · San Francisco, US
• John Salmeron · Hillsborough, US
• Caius Rommens · Boise, US

Key dates

• Filing date: Jul 11, 1996
• Grant date: Jan 12, 1999
• Expiry date: Jul 11, 2016

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C12N15/8279
• WIPO field: Biotechnology
• WIPO sector: Chemistry

Abstract

The Prf gene of tomato has been cloned and analyzed. Prf encodes a protein with leucine-rich repeat, nucleotide binding, and leucine zipper motifs, identifying it as a member of the resistance gene class that includes RPS2, RPM1, N and L6. When expressed in transgenic plants, Prf confers Fenthion sensitivity and resistance to a wide variety of phytopathogens, including not only Pseudomonas syringae but also unrelated pathogens such as Xanthomonas campestris.