Patent · US Expired

Monoclonal antibodies for detecting Norwalk virus

US5861241A · kind A · utility

28Cited by
1References
12Claims
0Family size

Assignee

Inventors

Key dates

Filing dateAug 15, 1996
Grant dateJan 19, 1999
Priority date
Expiry dateAug 15, 2016

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S977/918
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

Monoclonal antibodies and their use in assays to determine the presence of Norwalk virus, Norwalk virus particles, or Norwalk virus-specific IgM, in a biological sample. One assay includes the steps of contacting the sample with a monoclonal antibody that specifically binds to Norwalk virus particles in human stool; reacting the sample and the antibody for a time and under conditions that allow the formation of an immunocomplex between the antibody and any Norwalk virus in the sample; and detecting the immunocomplex, the presence of the immunocomplex indicating the presence of human Norwalk virus in the sample. Another assay is an IgM capture antibody immunoassay.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.