Patent · US Expired

Immobilization of specific binding assay reagents

US5861319A · kind A · utility

28Cited by
11References
36Claims
0Family size

Assignee

Inventors

Key dates

Filing dateOct 28, 1994
Grant dateJan 19, 1999
Priority date
Expiry dateOct 28, 2014

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S530/811
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

Methods and compositions are provided for specific binding assays in which specific binding reagents are immobilized on a solid phase. Immobilization is facilitated by covalently coupling specific binding assay reagents such as polypeptide receptors or analytes with water soluble polymers. Such water soluble polymers, for example star polymers such as dendrimers, provide production advantages of lot-to-lot uniformity and homogeneity, and can enhance sensitivity due to low non-specific binding to the solid phase.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.