Steroid sulphatase inhibitors
US5861390A · kind A · utility
3Cited by
2References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | May 31, 1995 |
| Grant date | Jan 19, 1999 |
| Priority date | — |
| Expiry date | May 31, 2015 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07J31/006
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Steroid sulphatase inhibitors and pharmaceutical compositions containing them for use in the treatment of oestrone dependent tumors, especially breast cancer. The steroid sulphatase inhibitors are phosphonate esters of formula (I) ##STR1## where R is alkyl, alkenyl, cycloalkyl or aryl; and --O--polycycle represents the residue of a polycyclic alcohol such as a sterol, preferably a 3-sterol.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.