Compounds useful for inhibition of farnesyl proteins transferase
US5861395A · kind A · utility
14Cited by
15References
32Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 11, 1997 |
| Grant date | Jan 19, 1999 |
| Priority date | — |
| Expiry date | Sep 11, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D401/14
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Novel compounds of the formula: ##STR1## are disclosed. Compounds of Formula 1.0 are represented by the compounds of formulas: ##STR2## wherein R.sup.1, R.sup.3 and R.sup.4 are each independently selected from halo. Also disclosed are methods of inhibiting farnesyl protein transferase and the growth of abnormal cells, such as tumor cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.