Purin-6-one derivatives

US5861396A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Ulrich Niewohner · Wermelskirchen, DE
• Erwin Bischoff · Wuppertal, DE
• Joachim Hutter · Leverkusen, DE
• Elisabeth Perzborn · Wuppertal, DE
• Helmuth Schutz · Regensburg, DE

Key dates

• Filing date: Oct 30, 1996
• Grant date: Jan 19, 1999
• Expiry date: Oct 30, 2016

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Purin-6-one derivatives are prepared by acylating appropriately substituted imidazole carboxamides and then cyclizing to give the purines. The purin-6-one derivatives are suitable as active compounds in medicaments, in particular for the treatment of cardiovascular disorders, disorders of the vascular system and of the urogenital system.