2,9-disubstituted purin-6-ones

US5861404A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Ulrich Niewohner · Wermelskirchen, DE
• Erwin Bischoff · Wuppertal, DE
• Helmuth Schutz · Regensburg, DE
• Elisabeth Perzborn · Wuppertal, DE
• Matthias Schramm · Cologne, DE

Key dates

• Filing date: Jan 12, 1996
• Grant date: Jan 19, 1999
• Expiry date: Jan 12, 2016

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P43/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

2,9-Disubstituted purin-6-ones are prepared by acylating correspondingly substituted aminoimidazoles in a first step and then cyclizing the product to the purine. The new 2,9-disubstituted purin-6-ones can be employed as active compounds in medicaments, in particular for the treatment of inflammations, thromboembolic and cardiovascular diseases and diseases of the urogenital system.