Treatment of pulmonary conditions associated with insufficient secretion of surfactant
US5863563A · kind A · utility
4Cited by
10References
36Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Oct 20, 1994 |
| Grant date | Jan 26, 1999 |
| Priority date | — |
| Expiry date | Oct 20, 2014 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61M2202/064
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Methods and compositions for the treatment of the symptoms of a patient who has a pulmonary condition associated with an inhibition of surfactant secretion by type II alveolar cells are described. The method of treatment involves causing a patient to inhale an amount of a pH-raising buffer effective to raise the pH of the aqueous fluid in the microenvironment of the type II alveolar cell lumenal surface, thereby inducing an increase in the rate of surfactant secretion by type II alveolar cells.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.