Preparation of saccharincarboxylic acids and -carboxylic acid esters

US5863864A · kind A · utility

Assignee

• BASF SE

Inventors

• Peter Plath · Bischofswerda, DE
• Harald Rang · Ludwigshafen, DE
• Karl-Otto Westphalen · Speyer, DE
• Matthias Gerber · Schifferstadt, DE
• Helmut Walter · Obrigheim, DE

Key dates

• Filing date: Feb 3, 1997
• Grant date: Jan 26, 1999
• Expiry date: Feb 3, 2017

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A01N43/80
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Saccharincarboxylic acids and -carboxylic acid esters of the formula I ##STR1## where the substituents have the following meanings: L and M are hydrogen, alkyl, alkoxy, alkylthio, chlorine, cyano, alkylsulfonyl, nitro or trifluoromethyl; PA0 Z is hydrogen, alkyl, cycloalkyl, alkyl, aryl or aralkyl; PA0 R is H or C.sub.1 -C.sub.6 -alkyl, are prepared by reacting corresponding bromo- or iodo-substituted saccharin derivatives of the formula II ##STR2## where L, M and Z have the abovementioned meanings, or if Z.noteq.H, compounds of the formula III ##STR3## in the presence of a palladium, nickel, cobalt or rhodium transition metal catalyst and of a base with carbon monoxide and water or a C.sub.1 -C.sub.6 -alcohol under elevated pressure.