Patent · US Expired

2',5'-phosphorothioate/phosphodiester oligoadenylates and anti-viral uses thereof

US5863905A · kind A · utility

5Cited by

13References

48Claims

0Family size

Assignee

Temple University-Of The Commonwealth System of Higher Education · US

Inventors

Robert J. Suhadolnik · Roslyn, US
Wolfgang Pfleiderer · Konstanz, DE

Key dates

Filing date	Jan 8, 1997
Grant date	Jan 26, 1999
Priority date	—
Expiry date	Jan 8, 2017

Classification

Technology area (CPC A)Human Necessities
CPC primaryA61P35/00
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Optically active antiviral compounds having the formula ##STR1## wherein m is 0, 1, 2, or 3; n and q are selected from the group of 0 and 1, provided that n and q may not both be zero; and R, R.sub.1, and R.sub.2 are independently of each other selected from the group consisting of oxygen and sulfur, provided that all R, R.sub.1 and R.sub.2, may not be oxygen, and further provided that all R, R.sub.1, and R.sub.2 may not be sulfur. The compounds possess increased antiviral activity and/or metabolic stability.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.