Bifunctional crown ether-based cation-exchange stationary phase for liquid chromatography
US5865994A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Mar 13, 1997 |
| Grant date | Feb 2, 1999 |
| Priority date | — |
| Expiry date | Mar 13, 2017 |
Classification
- Technology area (CPC B)Performing Operations; Transporting
- CPC primaryB01J45/00
- WIPO fieldChemical engineering
- WIPO sectorChemistry
Abstract
In accordance with the present invention, an improved bifunctional cation-exchange composition has been formed which comprises synthetic resin support particles and both crown ether and non-crown ether functional groups attached thereto. The compositions of the present invention provide for novel, enhanced cation separation capabilities and, depending upon the type of functional groups employed, permit effective separation of cations which elute at approximately the same time off standard and commonly used cation-exchange columns. The presently described bifunctional cation-exchange compositions also permit the effective separation of one cation from a mixture comprising another cation that is present at a significantly greater concentration. Formed articles and methods employing the bifunctional cation-exchange composition are also provided.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.