Compositions and methods for screening drug libraries
US5866341A · kind A · utility
36Cited by
8References
63Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 3, 1996 |
| Grant date | Feb 2, 1999 |
| Priority date | — |
| Expiry date | Apr 3, 2016 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2319/00
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A method of screening for binding partners of a specific molecule. The method employs a chimeric protein having at least two different binding regions; one containing at least a portion of the specific molecule or an analog thereof, and the other containing a binding region of an immunoglobulin chain. In a preferred embodiment, the method is used for rapidly screening member compounds of a combinatorial library for potential biological activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.