Nematode-extracted anticoagulant protein

US5866542A · kind A · utility

Assignee

• Corvas International, Inc. · US

Inventors

• George P. Vlasuk · Carlsbad, US
• Patrick Stanssens · Sint-Martens-Latem, BE
• Joris Hilda Lieven Messens · Dilbeek, BE
• Marc Jozef Lauwereys · Haaltert, BE
• Yves Rene LaRoche · Brussels, BE
• Laurent Jespers · Tervuren, BE
• Yannick George Jozef Gansemans · Bredene, BE
• Matthew Moyle · Redmond, US
• Peter W. Bergum · San Diego, US

Key dates

• Filing date: Jun 5, 1995
• Grant date: Feb 2, 1999
• Expiry date: Jun 5, 2015

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61K38/00
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Proteins which are potent anticoagulants and have at least one NAP domain and are described. These proteins having anticoagulant activity can be isolated from natural sources such as nematodes, chemically synthesized or made by recombinant methods using various DNA expression systems.