Epoxide-containing compounds
US5866576A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jan 3, 1997 |
| Grant date | Feb 2, 1999 |
| Priority date | — |
| Expiry date | Jan 3, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D473/10
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Disclosed are enantiomers, diastereomers, salts, solvates, hydrates and mixtures thereof, of formula I: ##STR1## The core moiety is a monocyclic ring structure having five to six ring atoms and two nitrogen atoms at the 1 and 3 positions, n is an integer from 4 to 16, R.sub.1 and R.sub.2 are hydrogen, halogen or C.sub.1-12 alkyl or alkenyl, and (CH.sub.2).sub.n may be optionally substituted by a hydroxyl, halogen, oxygen, a C.sub.1-4 alkyl group or a dimethylamino group. The compounds and pharmaceutical composition thereof are useful in methods for treating an individual having a disease or treatment-induced toxicity mediated through a second messenger.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.