Colonic drug delivery system
US5866619A · kind A · utility
Assignees
Inventors
Key dates
| Filing date | Nov 26, 1997 |
| Grant date | Feb 2, 1999 |
| Priority date | — |
| Expiry date | Nov 26, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08B37/0069
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A colonic delivery system for delivering a drug to the colon is provided. The system comprises a drug in combination with a matrix, wherein the matrix comprises a saccharide-containing polymer. According to the invention, the matrix is resistant to chemical and enzymatic degradation in the stomach and small intestine. The matrix is degraded in the colon by bacterial enzymatic action, and the drug is released. The system is useful for targeting drugs to the colon in order to treat colonic disease. The system is also useful for enteric administration of drugs such as proteins and peptides which are otherwise degraded in the stomach and small intestine.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.