Monoclonal antibodies to GP130 protein
US5866689A · kind A · utility
55Cited by
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17Claims
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Key dates
| Filing date | Feb 3, 1997 |
| Grant date | Feb 2, 1999 |
| Priority date | — |
| Expiry date | Feb 3, 2017 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07K2317/73
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Monoclonal antibodies recognizing gp130 protein and binding to the protein to inhibit IL-6 functions completely (that is to the same level as that is the absence of IL-6) when present in enough amount; a hybridoma producing the monoclonal antibody; a process for production of the monoclonal antibodies using the hybridoma; and an inhibitory agent for inhibition of physiological actions of IL-6 comprising the monoclonal antibodies.
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