Solid-phase synthesis of oligoribonucleotides

US5866700A · kind A · utility

Assignee

• Hoechst GmbH · DE

Inventors

• Wolfgang Pfleiderer · Konstanz, DE
• Ralf Schnell · Munich, DE
• Stephan Matysiak · Radolfzell, DE

Key dates

• Filing date: Mar 20, 1997
• Grant date: Feb 2, 1999
• Expiry date: Mar 20, 2017

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07H21/00
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

A process for the preparation of oligoribonucleotides of the formula ##STR1## in which n, L, BB, W, T, Y', U, C.sup.1 and C.sup.2 are as defined in the description, by solid-phase synthesis is described, as are intermediates of the oligoribonucleotides.