Dopamine transporter knockout mice
US5866756A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Oct 2, 1996 |
| Grant date | Feb 2, 1999 |
| Priority date | — |
| Expiry date | Oct 2, 2016 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA01K2267/0356
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A recombinant rodent comprises cells containing a pair of genomic dopamine transporter protein alleles, wherein at least one of said alleles is incapable of expressing endogenous dopamine transporter protein. The rodent may be a homozygote, where both of said alleles are incapable of expressing endogenous dopamine transporter protein, or the rodent may be a heterozygote, and one of said alleles expresses endogenous dopamine transporter protein. The rodent is preferably a mouse.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.